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To our know-how, This can be the first examine of desmetramadol in humans and the very first to point out it offers a similar security and analgesia as tramadol, but without tramadol’s metabolic liabilities and associated drug−drug interactions.

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“Neuropathic pain is especially challenging to deal with and patients in many cases are provided anti-depressants that potently inhibit metabolic activation of tramadol. Desmetramadol can be a novel Resolution close to this difficulty.”

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